Colotrin 

Colotrin 

CHONDROPROTECTORS

Presentation:

Box containing 60 tablets

Species:

Composition

Glucosamine hydrochloride 300 mg
Chondroitin sulfate 200 mg
Metilsulfonilmetane 500 mg
Excipients q.s. 3000 mg

Therapeutic Action

Chondroprotective, anti-inflammatory, joint regenerating drug.

Indications for Use

To be used in cats and dogs to treat primary and secondary inflammatory arthritis and other inflammatory processes of joints, such as tendonitis, synovitis and non-infectious arthritis.

Used to treat chondropathies, hydrarthrosis and osteoarthritis. It has joint anti-inflammatory properties and it functions as an adjuvant to promote fracture healing. It aids articular cartilage regeneration: By stimulating the synthesis of glycosaminoglycans.

It has a chondropotective effect: When administered orally, CS has a chondroprotective effect: it stimulates the synthesis of proteoglycans and collagen by chondrocytes, it normalizes synovial fluid and increases its viscosity. It also inhibits cartilage-degrading enzymes.

Combination therapy with NSAIDs: Synergy in the treatment of some types of acute pain. Since the anti-inflammatory activity of glucosamine is different from that of the NSAIDs, it is possible that the combined action of both reduces the dose of NSAIDs required to produce an anti-exudative effect.

Route of Administration

Oral

Dosage and Instructions for Use

Dogs: Up to 10 kg body weight: ½ tablet daily. Over 10 kg body weight: 1 tablet daily. Dogs over 30 kg body weight: initial dosage shall be determined by prescribing veterinary doctor.

Cats: Up to 5 kg body weight: ¼ tablet daily. Over 5 kg body weight: ½ tablet daily.

It is recommended that initial treatment is continued for 45-60 days (until an optimal response is reached), depending on the severity of the clinical features, which shall be assessed by the intervening professional. After this period, and at the Veterinary Surgeon’s discretion, a maintenance dose shall be established.

Contraindications / Warnings / Precautions

Do not use in case of known hypersensitivity to any components in the formulation. Do not use in pregnant or lactating animals.

Reported adverse effects were: gastric discomfort, constipation, diarrhea, tympanites and nausea, all of which were usually temporary.

Available

-Argentina.